Drexel. Our lab seeks to study the regulation and modulation of glutamate transporters in healthy and diseased states. Learn more.

Drexel. Our lab aims to understand the neurobiological bases of behavioral flexibility and cognitive control, and the mechanisms by which these processes are dysregulated in neuropsychiatric illnesses. Learn more.

Penn. Mechanisms of immune regulation and immune:CNS/glial interactions. MOA of Therapeutics targeting CNS inflammation. Biomarkers. Learn more.

Jefferson. Astrocyte-mediated plasticity mechanisms in injury/stroke. Learn more.

Penn. We study moderate-to-severe TBI with coma using head rotational acceleration in pigs, focusing on astrocyte pathology. We also focus on Tissue Engineered Rostral Migratory Stream to redirect neuroblasts from adult subventricular zone into brain lesions to provide sustained delivery and promote regeneration. Learn more.

Penn. We use exciting techniques to understand the origin and function of microglia and to advance microglial replacement therapies. Learn more.

Drexel. We study the role of astrocytes in the central nervous system. Through the lens of Sonic hedgehog signaling between neurons and astrocytes, we investigate its potential importance in mediating experience-dependent plasticity. Learn more.

Drexel. We examine the immunomodulatory impact of neurotransmitters, mostly dopamine, and substances of misuse on myeloid cells in disease. We primarily examine these effects in the context of HIV and inflammation. Learn more.

CHOP. Oligodendrocyte maturation and myelination during development and remyelination following demyelinating disease. Learn more.

Penn. We use in vitro and in vivo CRISPR screening approaches to ask questions about glial biology and neuroimmunology in the context of aging and neurodegenerative diseases. Learn more.

Nemours. We study pediatric epilepsy, trying to understand the role of astrocyte dysfunction and astrocyte-neuron dynamics in behavioral impairments that occur in epilepsy. Learn more.

Jefferson. We focus on molecular pathways underlying ALS, with an emphasis on the contribution of glia in driving disease progression. Using various in vitro and in vivo modeling systems, we aim to identify iand target candidates with therapeutic potential. Learn more.

Penn. We are interested in the role of neuroinflammation induced by HIV-infection of microglia on neuronal function and oligodendrocyte differentiation and myelination. We have been examining organellar response to neuroinflammation and HIV related stimuli. Learn more.

Temple. Glial progenitors and oligodendrocyte abnormalities in CNS diseases. Learn more.

Drexel. Persistence of HIV in the CNS and the issue of substance use. Learn more.

Jefferson. We study cellular mechanisms underlying the pathogenesis of traumatic spinal cord injury (SCI), specifically respiratory dysfunction and chronic neuropathic pain. We aim to develop cutting-edge therapeutic strategies that can be translated to individuals affected by SCI. Learn more.

CHOP. We study the form and function of microglia in pediatric neuroimmunological disease. Learn more.

Drexel. Neurological complications of neuroHIV. Learn more.

Nemours. We study the mechanisms of early life brain injury with an emphasis on neuroimmune mechanisms of injury and recovery. We are specifically interested in neonatal hypoxic ischemic brain injury and immunomodulatory technology. Learn more.

Penn. Role of glial cells in acquired and inherited disorders of myelin. Learn more

University of Delaware. Role of immune function / microglia in neurodevelopmental disorders and postpartum depression animal models. Learn more.

Jefferson. Immunopathogenesis of multiple sclerosis and other CNS inflammatory diseases. Learn more.

CHOP. Our long-term goal is to elucidate the cellular and molecular basis governing the formation, maintenance, and function of neural circuits under physiological and pathological conditions, working with fly and mammalian models. Learn more.

Drexel. We study cell death and plasticity after traumatic injury to the mature and immature brain. Learn more.

CHOP. We work on ex vivo and in vivo gene therapy technologies, focusing on genetic modifications of hematopoietic stem cells as well as brain cells. Learn more.

CHOP. Our translational research model is aimed at developing a robust understanding of leukodystrophies and other heritable conditions affecting the white matter of the brain. Learn more.